PTPN12 wt Allele

Preferred Label : PTPN12 wt Allele;

NCIt synonyms : PTPG1; PTP-PEST; Protein Tyrosine Phosphatase, Non-Receptor Type 12 wt Allele;

NCIt definition : Human PTPN12 wild-type allele is located in the vicinity of 7q11.23 and is approximately 103 kb in length. This allele, which encodes tyrosine-protein phosphatase non-receptor type 12 protein, plays a role in the dephosphorylation of protein-tyrosine phosphates. Defects in the PTPN12 gene are associated with colon cancer.;

GenBank Accession Number : NM_002835;

Details

Origin ID

C49520;

UMLS CUI

C1705342;

OMIM relation
- Protein-tyrosine phosphatase, nonreceptor-type, 12 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_associated_with_disease
- Colon Carcinoma [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 7q11.23 [NCIt concept]
gene_is_element_in_pathway
- Phosphatidylinositol Signaling System Pathway [NCIt concept]
gene_plays_role_in_process
- Cell Differentiation Process [NCIt concept]
- Cell Growth [NCIt concept]
- Cell Proliferation [NCIt concept]
- Dephosphorylation [NCIt concept]
- Hydrolysis [NCIt concept]
- Protein Dephosphorylation [NCIt concept]
- Protein-Protein Interaction [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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