CDK5 wt Allele

Preferred Label : CDK5 wt Allele;

NCIt synonyms : PSSALRE; Cell Division Kinase 5 Gene; Cyclin-Dependent Kinase 5 wt Allele;

NCIt definition : Human CDK5 wild-type allele is located within 7q36 and is approximately 4 kb in length. This allele, which encodes cyclin-dependent kinase 5 protein, is involved in cell cycle regulation.;

NCIt note : CDK5 contains a catalytic and a regulatory subunit and is involved in cell cycle control. Expressed predominantly in neurons, CDK5 belongs to the CDC2/CDKX subfamily, interacts with D1- and D3-type G1 cyclins, and phosphorylates histone H1, TAU, MAP2, NF-H, and NF-M.;

GenBank Accession Number : NM_004935;

Details

Origin ID

C49458;

UMLS CUI

C1707116;

OMIM relation
- Cyclin-dependent kinase 5 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 7: 150192644-150188547 [NCIt concept]
gene_in_chromosomal_location
- 7q36 [NCIt concept]
gene_is_element_in_pathway
- Alzheimer's Disease Pathway BioCarta [NCIt concept]
- Bioactive Peptide Signaling Pathway [NCIt concept]
- CK1/CDK5 Regulation Pathway [NCIt concept]
- FosB Drug-induction Pathway [NCIt concept]
- LIS1 Pathway [NCIt concept]
- MAP Kinase Downregulation Pathway [NCIt concept]
- Rac1 Cell Motility Signaling Pathway [NCIt concept]
- Reelin Signaling Pathway BioCarta [NCIt concept]
gene_plays_role_in_process
- Cell Cycle Process [NCIt concept]
- Cell Cycle Regulation Process [NCIt concept]
- Cytokinesis [NCIt concept]
- Neural Development [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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