CDK10 wt Allele

Preferred Label : CDK10 wt Allele;

NCIt synonyms : PISSLRE; Cyclin-Dependent Kinase (CDC2-like) 10 wt Allele;

NCIt definition : Human CDK10 wild-type allele is located within 16q24 and is approximately 61 kb in length. This allele, which encodes cyclin-dependent kinase 10 protein, plays a role in cell cycle progression and proliferation.;

NCIt note : CDK plays a pivotal role in the regulation of the eukaryotic cell cycle and are known to be essential for cell cycle progression. This kinase has been shown to play roles in cellular proliferation and its function is limited to cell cycle G2-M phase. A variety of different transcripts exist, resulting from cryptic splice sites, exon skipping, insertion of intronic sequences, and exon scrambling. The splicing of this gene is complex. At least three alternatively spliced variants of this gene exist, one of which contains multiple non-ATG translation initiation sites.;

GenBank Accession Number : NM_052987;

Details

Origin ID

C49453;

UMLS CUI

C1707112;

OMIM relation
- Cyclin-dependent kinase 10 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 16: 88280579-88290263 [NCIt concept]
gene_in_chromosomal_location
- 16q24 [NCIt concept]
gene_plays_role_in_process
- Cell Cycle Process [NCIt concept]
- Cell Cycle Regulation Process [NCIt concept]
- Cell Proliferation [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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