PPP3CA wt Allele

Preferred Label : PPP3CA wt Allele;

NCIt synonyms : PPP2B; CALNA1; Protein Phosphatase 3 (Formerly 2B), Catalytic Subunit, Alpha Isoform (Calcineurin A Alpha) wt Allele; CCN1; CNA1; CALNA; CNA; CALN;

NCIt definition : Human PPP3CA wild-type allele is located within 4q21-q24 and is approximately 324 kb in length. This allele, which encodes serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform protein, is involved in calcium-dependent, calmodulin-stimulated protein dephosphorylation. The PPP3CA gene is associated with susceptibility to cardiac hypertrophy.;

GenBank Accession Number : NM_000944;

Details

Origin ID

C49425;

UMLS CUI

C1706031;

OMIM relation
- Protein phosphatase 3, catalytic subunit, alpha isoform [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 4q21-q24 [NCIt concept]
gene_is_element_in_pathway
- Alzheimer's Disease Pathway KEGG [NCIt concept]
- Amyotrophic Lateral Sclerosis Pathway [NCIt concept]
- Apoptosis Pathway [NCIt concept]
- Axon Guidance Pathway [NCIt concept]
- B Cell Receptor Signaling Pathway [NCIt concept]
- BCR Immune Response Signaling Pathway [NCIt concept]
- BCR Signaling Pathway [NCIt concept]
- CK1/CDK5 Regulation Pathway [NCIt concept]
- Calcineurin Pathway [NCIt concept]
- Calcium-Mediated Signaling Pathway [NCIt concept]
- Fc Epsilon Receptor I Signaling Pathway BioCarta [NCIt concept]
- Formyl Peptide Receptor 1 Signaling Pathway [NCIt concept]
- G-Protein Signaling Pathway [NCIt concept]
- Long-Term Potentiation Pathway [NCIt concept]
- MAPK Signaling Pathway [NCIt concept]
- NFAT Pathway [NCIt concept]
- Natural Killer Cell-Mediated Cytotoxicity Pathway [NCIt concept]
- Nitric Oxide Signaling Pathway [NCIt concept]
- Oocyte Meiosis Pathway [NCIt concept]
- PGC1a Regulation Pathway [NCIt concept]
- Skeletal Myogenesis Pathway [NCIt concept]
- Synaptic Vesicle Endocytosis Pathway [NCIt concept]
- T Cell Receptor Signaling Pathway BioCarta [NCIt concept]
- T Cell Receptor Signaling Pathway KEGG [NCIt concept]
- T-Cell Antiapoptosis Pathway [NCIt concept]
- T-Cell Apoptosis Pathway [NCIt concept]
- VEGF Signaling Pathway [NCIt concept]
- Wnt Signaling Pathway KEGG [NCIt concept]
gene_plays_role_in_process
- Dephosphorylation [NCIt concept]
- Hydrolysis [NCIt concept]
- Protein Dephosphorylation [NCIt concept]
- Protein-Protein Interaction [NCIt concept]
- Signal Transduction [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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