GLS2 wt Allele

Preferred Label : GLS2 wt Allele;

NCIt synonyms : Glutaminase 2 (Liver, Mitochondrial) wt Allele; GA; Liver Mitochondrial Glutaminase Gene; LGA; hLGA; GA wt Allele;

NCIt definition : Human GLS2 wild-type allele is located within 12q13 and is approximately 17 kb in length. This allele, which encodes glutaminase liver isoform, mitochondrial protein, is involved in the hydrolysis if L-glutamine. Expression of the GLS2 gene is induced during acidosis.;

GenBank Accession Number : NM_013267;

Details

Origin ID

C49388;

UMLS CUI

C1704662;

Automatic exact mappings (from CISMeF team)
- Glutaminase 2 [OMIM gene]
- Wind [MedDRA LLT]
- flatulence [MeSH Descriptor]
- germacrene-A synthase activity [GO term]
- glutaryl-7-aminocephalosporanic-acid acylase activity [GO term]
Currated CISMeF NLP mapping
- Gas [LOINC System]
- Gas [MedDRA LLT]
- Gaseous substance (substance) [SNOMED CT concept]
- gas [MedlinePlus Topic]
- gas, nos [SNOMED Notion]
- gases [MeSH Descriptor]
- gases [MeSH concept]
False automatic mappings
- Beta-hemolytic Streptococcus, group A (organism) [SNOMED CT concept]
- Granuloma annulare [ICD-11 Subcategory]
OMIM relation
- Glutaminase 2 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 12: 55168448-55151004 [NCIt concept]
gene_in_chromosomal_location
- 12q13 [NCIt concept]
gene_is_element_in_pathway
- Alanine, Aspartate and Glutamate Metabolism Pathway [NCIt concept]
- Arginine and Proline Metabolism Pathway [NCIt concept]
- D-Glutamine and D-Glutamate Metabolism Pathway [NCIt concept]
- Proximal Tubule Bicarbonate Reclamation Pathway [NCIt concept]
gene_plays_role_in_process
- Hydrolysis [NCIt concept]

Keyword's position in hierarchy(ies) :

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