NCIt definition : Human PLCB3 wild-type allele is located within 11q13 and is approximately 16 kb in
length. This allele, which encodes 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase
beta 3 protein, plays a role in the hydrolysis of 1-phosphatidylinositol-4,5 biphosphate.
This results in the production of specific second messengers involved in signal transduction.;