Preferred Label : Recombinant DNA-L523S Vaccine;
NCIt synonyms : pVAX/L523S;
NCIt definition : A plasmid DNA encoding human L523S, an RNA-binding protein that belongs to the KOC
(K homology domain containing protein overexpressed in cancer) family, with potential
antineoplastic activity. Vaccination with L523S DNA may stimulate a cytotoxic T lymphocytes
(CTL) response against tumor cells that express the L523S protein. As an oncofetal
protein, L523S is normally expressed in early embryonic tissue, but is overexpressed
in certain cancer cell types.;
Origin ID : C49290;
UMLS CUI : C1709856;
Semantic type(s)
- concept_is_in_subset
- is_component_of_chemotherapy_regimen
