Lenograstim - CISMeF

Preferred Label : Lenograstim;

NCIt synonyms : Glycosylated Recombinant Granulocyte Colony-Stimulating Factor; Glycosylated Recombinant G-CSF;

NCIt definition : A glycosylated form of a recombinant therapeutic agent which is chemically identical to or similar to an endogenous human granulocyte colony-stimulating factor (G-CSF). Produced endogenously by monocytes, fibroblasts, and endothelial cells, G-CSF binds to and activates specific cell surface receptors, stimulating neutrophil progenitor proliferation and differentiation and selected neutrophil functions.;

UNII : 6WS4C399GB;

CAS number : 135968-09-1;

Drug name : Neutrogin; Granocyte;

Codes from synonyms : 300;

Details

Origin ID

C49234;

UMLS CUI

C0218640;

Automatic exact mappings (from CISMeF team)
- Granulocytes [LOINC component]
- colony stimulating factor 3 [HGNC gene]
- granulocytes [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Lenograstim [Substance BNPC]
- Lenograstim [MeSH Descriptor]
- Lenograstim (substance) [SNOMED CT concept]
- Product containing lenograstim (medicinal product) [SNOMED CT concept]
- lenograstim [ATC Code]
- lenograstim [International Nonproprietary Name]
- lenograstim [MeSH concept]
Validated automatic mappings to BTNT
- lenograstim [ATC Code]
chemical_or_drug_affects_cell_type_or_tissue
- Hematopoietic Stem Cell [NCIt concept]
chemical_or_drug_affects_gene_product
- GM-CSF Receptor [NCIt concept]
chemical_or_drug_has_mechanism_of_action
- Cytokine Receptor Activation [NCIt concept]
chemical_or_drug_has_physiologic_effect
- Positive Regulation of Cell Differentiation [NCIt concept]
- Receptor Activation Process [NCIt concept]
- Stimulation of Cell Proliferation [NCIt concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- HemOnc Agent Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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