" /> Hemiasterlin Analog E7974 - CISMeF





Preferred Label : Hemiasterlin Analog E7974;

NCIt synonyms : Hemiasterlin Analog 7974;

NCIt related terms : E-7974;

NCIt definition : An analog of the sponge-derived anti-microtubule tripeptide hemiasterlin with antimitotic and potential antineoplastic activities. Hemiasterlin analog E7974 binds to the Vinca domain on tubulin, resulting in inhibition of tubulin polymerization and microtubule assembly; depolymerization of existing microtubules; inhibition of mitosis; and inhibition of cellular proliferation. This agent may have more affinity for the beta-3 tubulin isotype.;

UNII : 1BO0C11BSH;

CAS number : 610787-07-0; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 610787-07-0 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : E7974;

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12/05/2024


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