NCIt definition : A general term that refers to a TNM finding of a primary tumor usually indicating
that the cancer is locally invasive. The definition of T3b TNM finding depends on
the specific type of cancer that it refers to; for example, for kidney cancer it refers
to a primary tumor that grossly extends into the vena cava below the diaphragm; for
cervical cancer it refers to a primary tumor that extends to the pelvic wall and/or
causes hydronephrosis or nonfunctioning kidney; for liver cancer it refers to a single
tumor or multiple tumors of any size involving a major branch of the portal vein or
hepatic vein.;