NCIt definition : A TNM finding indicating the spread of cancer to distant anatomic sites. The definition
of M1a TNM finding depends on the specific type of cancer that it refers to; for example,
for colorectal cancer it refers to metastasis confined to one organ or site (e.g.,
liver, lung, ovary, nonregional node); for prostate cancer it refers to metastasis
to non-regional lymph node(s); for bone cancer it refers to metastasis to the lung.;