MAGE-3.A1 Peptide Vaccine

Preferred Label : MAGE-3.A1 Peptide Vaccine;

NCIt synonyms : HLA-A1-Restricted MAGE-3 Peptide Vaccine; MAGE-3.A1; HLA-A1-Restricted MAGE-3 Peptide;

NCIt definition : A synthetic peptide cancer vaccine consisting of human leukocyte antigen HLA-A1-restricted peptide derived from human melanoma antigen 3 (MAGE-3) with potential immunostimulating and antineoplastic activities. Upon administration, MAGE-3.A1 peptide vaccine may stimulate the immune system to mount a cytotoxic T-cell (CTL) response against tumor cells expressing MAGE-3, resulting in tumor cell lysis. MAGE-3, a tumor-associated antigen (TAA), is overexpressed by a variety of cancer cell types.;

NCI Metathesaurus CUI : CL423799;

NSC code : 731578;

Details

Origin ID

C48632;

UMLS CUI

C2981200;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
chemical_or_drug_has_mechanism_of_action
- Antigen Sensitization [NCIt concept]
concept_is_in_subset
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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