Volociximab - CISMeF

Preferred Label : Volociximab;

NCIt synonyms : anti-a5-beta1 Integrin; Anti-alpha5-beta1 Integrin;

NCIt related terms : M200;

NCIt definition : A chimeric monoclonal antibody with potential antineoplastic activity. Volociximab binds to and inhibits the activity of alpha(5)beta(1) integrin, thereby inhibiting endothelial cell-cell interactions, endothelial cell-matrix interactions, and angiogenesis. (NCI05);

Alternative definition : NCI-GLOSS: A monoclonal antibody that is being studied in the treatment of some types of cancer. Monoclonal antibodies are made in the laboratory and can locate and bind to substances in the body, including cancer cells. Volociximab binds to a protein that is found on cells that line some tumor blood vessels. It is a type of angiogenesis inhibitor.;

UNII : 496K5Z02NW;

CAS number : 558480-40-3;

Molecule name : M200;

Codes from synonyms : CDR0000430652; CDR0000423255;

Details

Origin ID

C48426;

UMLS CUI

C1541160;

Currated CISMeF NLP mapping
- volociximab [MeSH concept]
- volociximab [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- volociximab [MeSH concept]
- volociximab [MeSH Supplementary Concept]
chemical_or_drug_has_mechanism_of_action
- Antigen Binding [NCIt concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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