pNGVL4a-Sig/E7(detox)/HSP70 DNA Vaccine

Preferred Label : pNGVL4a-Sig/E7(detox)/HSP70 DNA Vaccine;

NCIt synonyms : pNGVL4a-Sig E7 detox HSP70 DNA Vaccine;

NCIt definition : An antigen-specific DNA cancer vaccine consisting of the coding sequences of a signal peptide (pNGVL4a-Sig), a detox form of the human papillomavirus type 16 (HPV-16) antigen E7, and the heat shock protein 70 (HSP70). Upon administration, this vaccine may generate potent cytotoxic CD8( ) T-cell responses against E7-expressing tumor cells, resulting in tumor cell death.;

Details

Origin ID

C48418;

UMLS CUI

C1711127;

Semantic type(s)
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_target
- Protein E7, Human Papillomavirus Type 16 [NCIt concept]

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