Preferred Label : Monoclonal Antibody HuAFP31;
NCIt synonyms : MOAB HuAFP31; Monoclonal Antibody HuAPF31;
NCIt related terms : HuAFP31;
NCIt definition : A humanized monoclonal antibody directed against alpha fetoprotein with potential
antineoplastic activity. Upon administration, monoclonal antibody HuAFP31 (mAb HuAFP31)
binds to and stimulates a cytotoxic T lymphocyte (CTL) response against tumor cells
that express alpha fetoprotein.;
Alternative definition : NCI-GLOSS: A monoclonal antibody being studied in the treatment of several types of
cancer. Monoclonal antibodies are made in the laboratory and can locate and bind to
substances in the body, including cancer cells. HuAFP31 attaches to tumor cells that
make alpha fetoprotein (AFP). This makes it easier for T cells to find and kill the
tumor cells.;
Molecule name : hAFP-31;
Codes from synonyms : CDR0000560640;
Origin ID : C48407;
UMLS CUI : C1541524;
Semantic type(s)
- chemical_or_drug_has_mechanism_of_action
- concept_is_in_subset
