Preferred Label : Iloprost;
NCIt synonyms : Ciloprost; Iloprost Clathrate; Ventavis; Pentanoic Acid, 5-(hexahydro-5-hydroxy-4-(3-hydroxy-4-methyl-1-octen-6-ynyl)-2(1H)-pentalenylidene)-; (E)-(3aS,4R,5R,6aS)-Hexahydro-5-hydroxy-4-((E)-(3S,4RS)-3-hydroxy-4-methyl-1-octen-6-ynyl)-delta(sup
2(1H),delta)-pentalenevaleric Acid;
NCIt definition : A prostacyclin analogue with potential chemopreventive activity. Iloprost binds to
the prostacyclin receptor in various target cells, thereby causing vasodilation, inhibition
of platelet aggregation, and decreased tumor cell adhesion to endothelium among other
effects. Prostacyclin is a naturally occurring eicosanoid with anti-inflammatory,
antineoplastic, and anti-metastatic properties. (NCI05);
Alternative definition : NCI-GLOSS: A substance that is being studied in the prevention of lung cancer. It
belongs to the family of drugs called prostaglandin analogs.;
UNII : JED5K35YGL;
InChIKey : HIFJCPQKFCZDDL-ACWOEMLNSA-N;
CAS number : 78919-13-8;
Molecule name : ZK 36374;
Chemical formula : C22H32O4;
ChEBI ID : CHEBI:63916;
Codes from synonyms : CDR0000377710; 50743;
Origin ID : C48397;
UMLS CUI : C0079594;
Semantic type(s)
- UMLS correspondences (same concept)
- Validated automatic mappings to BTNT
- concept_is_in_subset
