NCIt definition : The hydrochloride salt form of prilocaine, an intermediate-acting local anesthetic
of the amide type chemically related to lidocaine. Prilocaine hydrochloride binds
to voltage-gated sodium ion channels in the neuronal membrane, thereby preventing
the permeability of sodium ions. This leads to a stabilization of the neuronal membrane
and inhibits depolarization and results in a reversible blockage of nerve impulse
generation and propagation along nerve fibres and subsequent reversible loss of sensation.;