Preferred Label : Cephradine Monohydrate;
NCIt definition : The monohydrate form of cephradine, a beta-lactam, first-generation cephalosporin
antibiotic with bactericidal activity. Cephradine monohydrate binds to and inactivates
penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell
wall. PBPs participate in the terminal stages of assembling the bacterial cell wall,
and in reshaping the cell wall during cell division. Inactivation of PBPs interferes
with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength
and rigidity. This results in the weakening of the bacterial cell wall and causes
cell lysis.;
UNII : FUC0D71IZN;
CAS number : 75975-70-1;
Drug name : Forticef;
Chemical formula : C16H19N3O4S.H2O;
Origin ID : C47971;
UMLS CUI : C1707345;
Currated CISMeF NLP mapping
- Semantic type(s)
- concept_is_in_subset
