Cephalexin Hydrochloride

Preferred Label : Cephalexin Hydrochloride;

NCIt definition : The hydrochloride salt form of cephalexin, a beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity. Cephalexin hydrochloride binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. PBPs participate in the terminal stages of assembling the bacterial cell wall, and in reshaping the cell wall during cell division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.;

UNII : 6VJE5G3D98;

InChIKey : YHJDZIQOCSDIQU-OEDJVVDHSA-N;

CAS number : 105879-42-3;

Drug name : Keftab;

Chemical formula : C16H17N3O4S.HCl.H2O;

Details

Origin ID

C47969;

UMLS CUI

C0919352;

Automatic exact mappings (from CISMeF team)
- cephalexin [MeSH Descriptor]
- cephalexin hydrochloride [MeSH concept]
Currated CISMeF NLP mapping
- CEFALEXIN HYDROCHLORIDE [SMS substance]
- Cefalexin hydrochloride (substance) [SNOMED CT concept]
- cephalexin hydrochloride [SNOMED Notion]
- cephalexin monohydrochloride [MeSH concept]
Semantic type(s)
- Antibiotic [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Cefalexin hydrochloride (substance) [SNOMED CT concept]
- cephalexin hydrochloride [SNOMED Notion]
- cephalexin hydrochloride [MeSH concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_free_acid_or_base_form
- Cephalexin [NCIt concept]
is_salt_form_of
- Cephalexin [NCIt concept]

Keyword's position in hierarchy(ies) :

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