Zolmitriptan - CISMeF

Preferred Label : Zolmitriptan;

NCIt synonyms : 2-Oxazolidinone, 4-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)methyl)-,(S)-;

NCIt definition : A member of the triptan class of agents with anti-migraine properties. Zolmitriptan selectively binds to and activates serotonin (5-HT) 1B receptors expressed in intracranial arteries and 5-HT 1D receptors located on peripheral trigeminal sensory nerve terminals in the meninges and central terminals in brainstem sensory nuclei. Receptor binding results in constriction of cranial vessels, reduction of vessel pulsation and inhibition of nociceptive transmission, thereby providing relief of migraine headaches. Zolmitriptan may also relieve migraine headaches by inhibition of pro-inflammatory neuropeptide release.;

UNII : 2FS66TH3YW;

InChIKey : ULSDMUVEXKOYBU-ZDUSSCGKSA-N;

CAS number : 139264-17-8;

Drug name : Zomig;

Molecule name : 311C90;

Chemical formula : C16H21N3O2;

ChEBI ID : CHEBI:10124;

Details

Origin ID

C47789;

UMLS CUI

C0528166;

Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Product containing zolmitriptan (medicinal product) [SNOMED CT concept]
- ZOLMitriptan [LOINC component]
- Zolmitriptan (substance) [SNOMED CT concept]
- zolmitriptan [ATC Code]
- zolmitriptan [MeSH concept]
- zolmitriptan [MeSH Supplementary Concept]
Validated automatic mappings to BTNT
- zolmitriptan [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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