" /> Valsartan - CISMeF





Preferred Label : Valsartan;

NCIt synonyms : N-(p-(o-1H-Tetrazol-5-ylphenyl)benzyl)-N-valeryl-L-valine; L-Valine, N-(1-oxopentyl)-N-((2'-(1H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)-;

NCIt definition : An orally active nonpeptide triazole-derived antagonist of angiotensin (AT) II with antihypertensive properties. Valsartan selectively and competitively blocks the binding of angiotensin II to the AT1 subtype receptor in vascular smooth muscle and the adrenal gland, preventing AT II-mediated vasoconstriction, aldosterone synthesis and secretion, and renal reabsorption of sodium, and resulting in vasodilation, increased excretion of sodium and water, a reduction in plasma volume, and a reduction in blood pressure.;

UNII : 80M03YXJ7I;

InChIKey : ACWBQPMHZXGDFX-QFIPXVFZSA-N;

CAS number : 137862-53-4; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 137862-53-4 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Diovan;

Molecule name : CGP 48933;

Chemical formula : C24H29N5O3;

ChEBI ID : CHEBI:9927;

Codes from synonyms : 32063;

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21/05/2024


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