Preferred Label : Tubocurarine Chloride;
NCIt synonyms : Amerizol; 2,3,13a,14,15,16,25,25a-Octahydro-9,19-dihydroxy-18,29-dimethoxy-1,14,14-trimethyl-,
Chloride, Hydrochloride,(13aR,25aS)-; 13H-4,6:21,24-Dietheno-8,12-metheno-1H-pyrido(3',2':14,15)(1,11)dioxacycloeicosino(2,3,4-ij)isoquinolinium; Tubocuraranium, 7',12'-Dihydroxy-6,6'-dimethoxy-2,2',2'-trimethyl-, Chloride, Hydrochloride; d-Tubocurarine Chloride Pentahydrate; Tubocuraranium, 7',12'-Dihydroxy-6,6'-dimethoxy-2,2',2'-trimethyl-, Chloride, Hydrochloride,
Pentahydrate; Tubocurarine, Dichloride, Pentahydrate, ( )-;
NCIt definition : The chloride salt form of tubocurarine, a naturally occurring curare alkaloid isolated
from the bark and stem of Chondodendron tomentosum with a muscle relaxant property.
Tubocurarine chloride competes with acetylcholine for the nicotinic receptors at the
neuromuscular junction of skeletal muscles, thereby inhibiting the action of acetylcholine
and blocking the neural transmission without depolarizing the postsynaptic membrane.
This may lead to skeletal muscle relaxation and paralysis.;
UNII : 900961Z8VR;
InChIKey : WMIZITXEJNQAQK-GGDSLZADSA-N;
CAS number : 6989-98-6;
Drug name : Tubocurare;
Chemical formula : C37H41N2O6.Cl.HCl.5H2O;
NSC code : 36387;
Origin ID : C47777;
UMLS CUI : C0282372;
Semantic type(s)
- Validated automatic mappings to NTBT
- concept_is_in_subset
