Trimethadione - CISMeF

Preferred Label : Trimethadione;

NCIt synonyms : 2,4-Oxazolidinedione, 3,5,5-trimethyl-;

NCIt definition : A dione-type anticonvulsant with antiepileptic activity. Trimethadione reduces T-type calcium currents in thalamic neurons, thereby stabilizing neuronal membranes, raising the threshold for repetitive activities in the thalamus and inhibiting corticothalamic transmission. This decreases the abnormal thalamocortical rhythmicity, which is thought to underlie the paroxysmal three-cycle-per-second spike-and-wave pattern seen with absence (petit mal) seizures.;

UNII : R7GV3H6FQ4;

InChIKey : IRYJRGCIQBGHIV-UHFFFAOYSA-N;

CAS number : 127-48-0;

Drug name : Tridione;

Chemical formula : C6H9NO3;

NSC code : 15799;

Details

Origin ID

C47772;

UMLS CUI

C0041038;

Automatic exact mappings (from CISMeF team)
- Trimethadione [ICHI extension code]
See also inter- (CISMeF)
- Product containing trimethadione (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Product containing trimethadione (medicinal product) [SNOMED CT concept]
- Trimethadione [ICD-11 Extension code]
- Trimethadione [LOINC component]
- Trimethadione (substance) [SNOMED CT concept]
- trimethadione [ATC Code]
- trimethadione [Substance BNPC]
- trimethadione [MeSH Descriptor]
- trimethadione [MeSH concept]
- trimethadione [SNOMED Notion]
Validated automatic mappings to BTNT
- trimethadione [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

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