Travoprost - CISMeF

Preferred Label : Travoprost;

NCIt synonyms : 5-Heptenoic Acid, 7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((1E,3R)-3-hydroxy-4-(3-(trifluoromethyl)phenoxy)-1-butenyl)cyclopentyl)-, 1-methylethyl Ester,(5Z)-;

NCIt definition : A synthetic lipophilic isopropyl ester prodrug of the active compound travoprost free acid, a prostaglandin F2alpha analog with anti-glaucoma property. Upon administration, travoprost is hydrolysed to a free acid by corneal esterases, and then selectively stimulating the prostaglandin F (FP prostanoid) receptor, thereby increasing the uveoscleral outflow which leads to a reduction in intra-ocular pressure.;

UNII : WJ68R08KX9;

InChIKey : MKPLKVHSHYCHOC-AHTXBMBWSA-N;

CAS number : 157283-68-6;

Drug name : Travatan Z;

Molecule name : AL-6221;

Chemical formula : C26H35F3O6;

ChEBI ID : CHEBI:746859;

Details

Origin ID

C47766;

UMLS CUI

C0937916;

CISMeF manual mappings
- Travoprost [MeSH Descriptor]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Product containing travoprost (medicinal product) [SNOMED CT concept]
- Travoprost [MeSH Descriptor]
- Travoprost (substance) [SNOMED CT concept]
- travoprost [ATC Code]
- travoprost [Substance BNPC]
- travoprost [MeSH concept]
Validated automatic mappings to BTNT
- travoprost [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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