Tranexamic Acid

Preferred Label : Tranexamic Acid;

NCIt synonyms : Tranhexamic Acid; Cyclohexanecarboxylic Acid, 4-(aminomethyl)-, trans-;

NCIt definition : A synthetic derivative of the amino acid lysine with antifibrinolytic activity. With strong affinity for the five lysine-binding sites of plasminogen, tranexamic acid competitively inhibits the activation of plasminogen to plasmin, resulting in inhibition of fibrinolysis; at higher concentrations, this agent noncompetitively inhibits plasmin. This agent has a longer half-life, is approximately ten times more potent, and is less toxic than aminocaproic acid, which possesses similar mechanisms of action.;

UNII : 6T84R30KC1;

InChIKey : GYDJEQRTZSCIOI-LJGSYFOKSA-N;

CAS number : 1197-18-8;

Drug name : Cyclokapron; Cyklokapron; Lysteda; Amixam; Tranofast; Prexam; Hemostan;

Chemical formula : C8H15NO2;

NSC code : 291305;

ChEBI ID : CHEBI:48669;

Codes from synonyms : 509;

Details

Origin ID

C47765;

UMLS CUI

C0040613;

Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Product containing tranexamic acid (medicinal product) [SNOMED CT concept]
- Tranexamic acid [ICD-11 Extension code]
- Tranexamic acid (substance) [SNOMED CT concept]
- tranexamic acid [ATC Code]
- tranexamic acid [Substance BNPC]
- tranexamic acid [MeSH Descriptor]
- tranexamic acid [MeSH concept]
Validated automatic mappings to BTNT
- tranexamic acid [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- HemOnc Agent Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt COVID-19 Agent Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients