Tiopronin - CISMeF

Preferred Label : Tiopronin;

NCIt synonyms : Thiolpropionamidoacetic Acid; Glycine, N-(2-mercapto-1-oxopropyl)-; (2-Mercaptopropionyl)glycine;

NCIt definition : An acylated sulfhydryl-containing derivative of glycine with reducing and complexing properties. Tiopronin breaks the disulphide bond of cystine and binds the sulfhydryl group of the resultant cysteine monomers to form a soluble tiopronin-cysteine-mixed disulfide, which is more water-soluble than cystine and is readily excreted. This leads to a reduction in urinary cystine concentration and subsequently reduces cystine stone formation.;

UNII : C5W04GO61S;

InChIKey : YTGJWQPHMWSCST-UHFFFAOYSA-N;

CAS number : 1953-02-2;

Drug name : Thiola;

Chemical formula : C5H9NO3S;

Details

Origin ID

C47758;

UMLS CUI

C0025405;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Product containing tiopronin (medicinal product) [SNOMED CT concept]
- Tiopronin [ICD-11 Extension code]
- Tiopronin (substance) [SNOMED CT concept]
- tiopronin [ATC Code]
- tiopronin [Substance BNPC]
- tiopronin [MeSH concept]
- tiopronin [MeSH Descriptor]
Validated automatic mappings to BTNT
- tiopronin [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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