Sulfamethizole

Preferred Label : Sulfamethizole;

NCIt synonyms : 2-(p-Aminobenzenesulfonamido)-5-methylthiadiazole; N(sup 1)-(5-Methyl-1,3,4-thiadiazol-2-yl)sulfanilamide; 4-Amino-N-(5-methyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide;

NCIt definition : A broad-spectrum sulfanilamide and a synthetic analog of para-aminobenzoic acid (PABA) with antibacterial property. Sulfamethizole competes with PABA for the bacterial enzyme dihydropteroate synthase, thereby preventing the incorporation of PABA into dihydrofolic acid, the immediate precursor of folic acid. This leads to an inhibition of bacterial folic acid synthesis and de novo synthesis of purines and pyrimidines, ultimately resulting in cell growth arrest and cell death.;

UNII : 25W8454H16;

InChIKey : VACCAVUAMIDAGB-UHFFFAOYSA-N;

CAS number : 144-82-1;

Drug name : Microsul; Proklar; Thiosulfil;

Chemical formula : C9H10N4O2S2;

ChEBI ID : CHEBI:9331;

Details

Origin ID

C47736;

UMLS CUI

C0038687;

Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Product containing sulfamethizole (medicinal product) [SNOMED CT concept]
- Sulfamethizole [LOINC component]
- Sulfamethizole [ICD-11 Extension code]
- Sulfamethizole (substance) [SNOMED CT concept]
- Sulphamethizole [ICD-11 Extension code]
- sulfamethizole [ATC Code]
- sulfamethizole [ATC Code]
- sulfamethizole [ATC Code]
- sulfamethizole [ATC Code]
- sulfamethizole [Substance BNPC]
- sulfamethizole [MeSH concept]
- sulfamethizole [MeSH Descriptor]
- sulfamethizole [SNOMED Notion]
Validated automatic mappings to BTNT
- sulfamethizole [ATC Code]
- sulfamethizole [ATC Code]
- sulfamethizole [ATC Code]
- sulfamethizole [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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