Sulfacytine - CISMeF

Preferred Label : Sulfacytine;

NCIt synonyms : Benzenesulfonamide, 4-amino-N-(1-ethyl-1,2-dihydro-2-oxo-4-pyrimidinyl)-; 1-Ethyl N4-sulfanilylcytosin; Sulfanilamide, N1-(1-ethyl-1,2-dihydro-2-oxo-4-pyrimidinyl)-(8CI);

NCIt definition : A short-acting, broad-spectrum sulfonamide and a synthetic analog of para-aminobenzoic acid (PABA) with bacteriostatic property. Sulfacytine competes with PABA for the bacterial enzyme dihydropteroate synthase, thereby preventing the incorporation of PABA into dihydrofolic acid, the immediate precursor of folic acid. This leads to an inhibition of bacterial folic acid synthesis and de novo synthesis of purines and pyrimidines, ultimately resulting in cell growth arrest and cell death.;

UNII : T795873AJP;

InChIKey : SIBQAECNSSQUOD-UHFFFAOYSA-N;

CAS number : 17784-12-2; 1401-49-6;

Drug name : Renoquid;

Chemical formula : C12H14N4O3S;

NSC code : 356717;

Details

Origin ID

C47734;

UMLS CUI

C0262960;

Currated CISMeF NLP mapping
- Sulfacitine [ICD-11 Extension code]
- Sulfacitine [ICHI extension code]
- Sulfacytine (substance) [SNOMED CT concept]
- sulfacytine [MeSH concept]
- sulfacytine [MeSH Supplementary Concept]
- sulfacytine [SNOMED Notion]
Semantic type(s)
- Antibiotic [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Sulfacitine [ICD-11 Extension code]
- Sulfacytine (substance) [SNOMED CT concept]
- sulfacytine [MeSH concept]
- sulfacytine [SNOMED Notion]
- sulfacytine [MeSH Supplementary Concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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