NCIt definition : A synthetic C-terminal octapeptide identical to the sequences of the endogenous cholecystokinin
hormone. Mimic action of cholecystokinin, sincalide induces gallbladder smooth muscle
contraction directly, thereby reducing gallbladder size, inducing bile evacuation,
and secretion of pancreatic enzymes. In addition, this agent decreases esophageal
sphincter tone and delays gastric emptying via cholinergic signaling.;