" /> Sibutramine Hydrochloride - CISMeF





Preferred Label : Sibutramine Hydrochloride;

NCIt synonyms : Cyclobutanemethanamine, 1-(4-chlorophenyl)-N,N-dimethyl-alpha-(2-methylpropyl)-, Hydrochloride;

NCIt definition : The hydrochloride salt form of sibutramine, a phenethylamine derivative with appetite depressant property. Sibutramine hydrochloride metabolites M1 and M2 competitively inhibit the reuptake of norepinephrine, serotonin, and to a lesser degree dopamine by pre-synaptic nerve terminals, thereby promoting a sense of satiety, leading to a decrease in calorie intake, and possibly an increase in resting metabolic rate. This agent does not exhibit anticholinergic or antihistaminic effects.;

UNII : OGM0YHD1WF;

InChIKey : KFNNPQDSPLWLCX-UHFFFAOYSA-N;

CAS number : 125494-59-9;

Drug name : Meridia;

Molecule name : BTS 54524; HSDB 7209;

Chemical formula : C17H26ClN.HCl.H2O;

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05/07/2025


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