Quetiapine Fumarate

Preferred Label : Quetiapine Fumarate;

NCIt synonyms : Ethanol, 2-(2-(4-dibenzo(b,f)(1,4)thiazepin-11-yl-1-piperazinyl)ethoxy)-,(E)-2-butenedioate(2:1)(salt);

NCIt definition : The fumarate salt form of quetiapine, a dibenzothiazepine derivative with antipsychotic property. Quetiapine fumarate antagonizes serotonin activity mediated by 5-HT 1A and 5-HT2 receptors. With a lower affinity, this agent also reversibly binds to dopamine D1 and D2 receptors in the mesolimbic and mesocortical areas of the brain leading to decreased psychotic effects, such as hallucinations and delusions. In addition, quetiapine fumarate also binds to other alpha-1, alpha-2 adrenergic and histamine H1 receptors.;

UNII : 2S3PL1B6UJ;

InChIKey : ZTHJULTYCAQOIJ-WXXKFALUSA-N;

CAS number : 111974-72-2;

Drug name : Seroquel XR;

Chemical formula : 2C21H25N3O2S.C4H4O4;

ChEBI ID : CHEBI:8708;

Details

Origin ID

C47700;

UMLS CUI

C0724680;

CISMeF manual mappings
- Quetiapine Fumarate [MeSH Descriptor]
Currated CISMeF NLP mapping
- Quetiapine fumarate [Substance BNPC]
- Quetiapine fumarate [SMS substance]
- Quetiapine fumarate (substance) [SNOMED CT concept]
- quetiapine fumarate [MeSH concept]
- quetiapine fumarate [International Nonproprietary Name]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Quetiapine Fumarate [MeSH Descriptor]
- Quetiapine fumarate [Substance BNPC]
- Quetiapine fumarate (substance) [SNOMED CT concept]
- quetiapine fumarate [International Nonproprietary Name]
- quetiapine fumarate [MeSH concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_free_acid_or_base_form
- Quetiapine [NCIt concept]
is_salt_form_of
- Quetiapine [NCIt concept]

Keyword's position in hierarchy(ies) :

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