Quazepam - CISMeF

Preferred Label : Quazepam;

NCIt synonyms : Selepam; Dormalin; 2H-1,4-Benzodiazepine-2-thione, 7-chloro-5-(2-fluorophenyl)-1,3-dihydro-1-(2,2,2-trifluoroethyl)-;

NCIt definition : A synthetic benzodiazepine derivative with anxiolytic, sedative and hypnotic properties. Quazepam and its major metabolite 2-oxoquazepam potentiate gamma-aminobutyric acid (GABA) activity by binding to the benzodiazepine-1 recognition site (BZ-1) within the GABA-A receptor, located in the limbic, neocortical and mesencephalic reticular system. This increases the frequency of GABA-activated chloride channel opening events, allowing the flow of chloride ions into the neuron leading to membrane hyperpolarization and decreased neuronal excitability.;

UNII : JF8V0828ZI;

InChIKey : IKMPWMZBZSAONZ-UHFFFAOYSA-N;

CAS number : 36735-22-5;

Drug name : Doral;

Chemical formula : C17H11ClF4N2S;

NSC code : 309702;

Details

Origin ID

C47699;

UMLS CUI

C0072828;

See also inter- (CISMeF)
- Product containing quazepam (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Product containing quazepam (medicinal product) [SNOMED CT concept]
- Quazepam [ICD-11 Extension code]
- Quazepam [LOINC component]
- Quazepam (substance) [SNOMED CT concept]
- quazepam [ATC Code]
- quazepam [Substance BNPC]
- quazepam [MeSH concept]
- quazepam [MeSH Supplementary Concept]
Validated automatic mappings to BTNT
- quazepam [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients