Preferred Label : Pyrithione Zinc;
NCIt synonyms : Zinc Pyridine-2-thiol 1-oxide; 2-Mercaptopyridine 1-oxide Zinc Salt; Bis(1-hydroxy-2(1H)-pyridinethionato)zinc; Zinc, bis(2-pyridylthio)-, N,N'-dioxide; Zinc, bis(1-hydroxy-2(1H)-pyridinethionato)-; Zinc Pyrithione;
NCIt definition : A coordination complex of the zinc ion and pyrithione, a derivative of the naturally
occurring antibiotic aspergillic acid with antimicrobial, antifungal and anti-seborrheic
effects. Although the exact mechanism of action remains to be fully elucidated, pyrithione
zinc appears to interfere with the membrane transport of ions and metabolites, ultimately
leading to a loss of metabolic control. In addition, this agent causes an influx of
copper, leading to a reduction in the activity of iron-sulphur proteins resulting
in growth inhibition.;
UNII : R953O2RHZ5;
InChIKey : OTPSWLRZXRHDNX-UHFFFAOYSA-L;
CAS number : 13463-41-7; 3590-23-6;
Chemical formula : 2C5H4NOS.Zn;
NSC code : 290409;
ChEBI ID : CHEBI:32076;
Origin ID : C47698;
UMLS CUI : C0078792;
Currated CISMeF NLP mapping
- See also inter- (CISMeF)
- Semantic type(s)
- UMLS correspondences (same concept)
- Validated automatic mappings to BTNT
- concept_is_in_subset
