NCIt definition : The sulfate salt form of pseudoephedrine, a phenethylamine and a diastereomer of ephedrine
with sympathomimetic property. Pseudoephedrine sulfate displaces norepinephrine from
storage vesicles in presynaptic neurones, thereby releasing norepinephrine into the
neuronal synapses where it stimulates primarily alpha-adrenergic receptors. It also
has weak direct agonist activity at alpha- and beta- adrenergic receptors. Receptor
stimulation results in vasoconstriction and decreases nasal and sinus congestion.;