Promazine Hydrochloride

Preferred Label : Promazine Hydrochloride;

NCIt synonyms : Starazin; Talofen; Sparine; 10H-Phenothiazine-10-propanamine, N,N-dimethyl-, Monohydrochloride; 10-(3-(Dimethylamino)propyl)phenothiazine Monohydrochloride;

NCIt definition : The hydrochloride salt form of promazine, a phenothiazine derivative with antipsychotic and antiemetic properties. Promazine hydrochloride blocks postsynaptic dopamine receptors D1 and D2 in the mesolimbic and medullary chemoreceptor trigger zone (CTZ), thereby decreasing stimulation of the vomiting center in the brain and psychotic effects, such as hallucinations and delusions. In addition, this agent blocks alpha-adrenergic receptors and exhibits strong anticholinergic activity.;

UNII : U16EOR79U4;

InChIKey : JIVSXRLRGOICGA-UHFFFAOYSA-N;

CAS number : 53-60-1;

Chemical formula : C17H20N2S.HCl;

NSC code : 17468;

ChEBI ID : CHEBI:8460;

Details

Origin ID

C47691;

UMLS CUI

C0546875;

Automatic exact mappings (from CISMeF team)
- Sparine [ICHI extension code]
- sparine [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Promazine hydrochloride [Substance BNPC]
- Promazine hydrochloride (substance) [SNOMED CT concept]
- promazine hydrochloride [MeSH concept]
- promazine hydrochloride [SNOMED Notion]
Validated automatic mappings to BTNT
- Sparine [ICD-11 Extension code]
Validated automatic mappings to NTBT
- promazine [MeSH Descriptor]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_free_acid_or_base_form
- Promazine [NCIt concept]
is_salt_form_of
- Promazine [NCIt concept]

Keyword's position in hierarchy(ies) :

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