Procyclidine Hydrochloride

Preferred Label : Procyclidine Hydrochloride;

NCIt synonyms : Kemadrin; Tricyclamol Hydrochloride; 1-cyclohexyl-1-phenyl-3-pyrrolidino-1-propanol Hydrochloride; 1-Pyrrolidinepropanol, alpha-cyclohexyl-alpha-phenyl-, Hydrochloride;

NCIt definition : The hydrochloride salt form of procyclidine, with anticholinergic properties. Procyclidine hydrochloride competitively binds to striatal cholinergic receptors, thereby diminishing acetylcholine activity and ultimately reducing the frequency and severity of akinesia, rigidity, and tremor associated with uncontrollable body movements. In addition, this agent may block the re-uptake of dopamine by nerve terminals, thereby increasing dopamine activity.;

UNII : CQC932Z7YW;

InChIKey : ZFSPFXJSEHCTTR-UHFFFAOYSA-N;

CAS number : 1508-76-5;

Chemical formula : C19H29NO.HCl;

NSC code : 169103;

ChEBI ID : CHEBI:8449;

Details

Origin ID

C47689;

UMLS CUI

C0546874;

Currated CISMeF NLP mapping
- Procyclidine Hydrochloride [MeSH concept]
- Procyclidine hydrochloride [Substance BNPC]
- Procyclidine hydrochloride (substance) [SNOMED CT concept]
- procyclidine hydrochloride [SNOMED Notion]
See also inter- (CISMeF)
- kemadrin [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Procyclidine Hydrochloride [MeSH concept]
- Procyclidine hydrochloride [Substance BNPC]
- Procyclidine hydrochloride (substance) [SNOMED CT concept]
- procyclidine hydrochloride [SNOMED Notion]
Validated automatic mappings to NTBT
- procyclidine [MeSH Descriptor]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_free_acid_or_base_form
- Procyclidine [NCIt concept]
is_salt_form_of
- Procyclidine [NCIt concept]

Keyword's position in hierarchy(ies) :

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