NCIt definition : The hydrochloride salt form of procaine, a benzoic acid derivative with local anesthetic
and antiarrhythmic properties. Procaine binds to and inhibits voltage-gated sodium
channels, thereby inhibiting the ionic flux required for the initiation and conduction
of impulses. In addition, this agent increases electrical excitation threshold, reduces
rate of rise of action potential and slows nerve impulse propagation thereby causing
loss of sensation.;