Potassium Perchlorate

Preferred Label : Potassium Perchlorate;

NCIt synonyms : Perchloric Acid, Potassium Salt; Astrumal;

NCIt definition : The potassium salt of perchloric acid and a member of the Hofmeister ions series with thyroid blocking properties. Potassium perchlorate is a competitive inhibitor of iodine uptake through inhibiting the sodium-iodide symporter (NIS) on the thyroid follicular cell membrane. This results in a potential decrease in thyroid hormone synthesis including thyroxine (T4) and tri-iodothyronine (T3). In addition, this agent decreases the accumulation of the radioactive imaging substance and Hofmeister series ion, pertechnetate Tc 99m, in the choroid plexus and in the salivary and thyroid glands through competitive displacing.;

UNII : 42255P5X4D;

InChIKey : YLMGFJXSLBMXHK-UHFFFAOYSA-M;

CAS number : 7778-74-7;

Drug name : Perchloracap;

Chemical formula : ClO4.K;

NSC code : 41873;

Details

Origin ID

C47681;

UMLS CUI

C0071774;

Automatic exact mappings (from CISMeF team)
- Potassium perchlorate nonmedicinal [ICD-11 Extension code]
- Talus [LOINC System]
- astragalus plant [MeSH Descriptor]
- talus [MeSH Descriptor]
Currated CISMeF NLP mapping
- Potassium perchlorate [SMS substance]
- Potassium perchlorate (substance) [SNOMED CT concept]
- Product containing potassium perchlorate (medicinal product) [SNOMED CT concept]
- potassium perchlorate [Substance BNPC]
- potassium perchlorate [MeSH concept]
- potassium perchlorate [MeSH Supplementary Concept]
- potassium perchlorate [SNOMED Notion]
Manual BTNT mappings - CISMeF
- Potassium perchlorate antithyroid [ICD-11 Extension code]
- Potassium perchlorate medicinal [ICD-11 Extension code]
Semantic type(s)
- Inorganic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Potassium perchlorate (substance) [SNOMED CT concept]
- Product containing potassium perchlorate (medicinal product) [SNOMED CT concept]
- potassium perchlorate [ATC Code]
- potassium perchlorate [Substance BNPC]
- potassium perchlorate [MeSH concept]
- potassium perchlorate [SNOMED Notion]
- potassium perchlorate [MeSH Supplementary Concept]
Validated automatic mappings to BTNT
- potassium perchlorate [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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