NCIt definition : The acetate salt form of pirbuterol, a synthetic catecholamine and a pyridine derivative
with sympathomimetic and bronchodilatory effects. Pirbuterol acetate selectively stimulates
beta-2 adrenergic receptors, resulting in initiation of intracellular adenylate cyclase
activity leading to increased levels of cAMP. As a result muscle relaxation (broncho-
and vasodilation) occurs via cAMP-dependent signal transduction. In addition, elevated
levels of cAMP inhibit release of inflammatory mediators from mast cells.;