Pimozide - CISMeF

Preferred Label : Pimozide;

NCIt synonyms : Opiran; 2H-Benzimidazol-2-one, 1-(1-(4,4-bis(4-fluorophenyl)butyl)-4-piperidinyl)-1,3-dihydro-;

NCIt definition : A diphenylbutylpiperidine derivative and a dopamine antagonist with antipsychotic property. Pimozide selectively inhibits type 2 dopaminergic receptors in the central nervous system (CNS), thereby decreasing dopamine neurotransmission and reducing the occurrence of motor and vocal tics and delusions of parasitosis. In addition, this agent antagonizes alpha-adrenergic and 5-HT2 receptors.;

UNII : 1HIZ4DL86F;

InChIKey : YVUQSNJEYSNKRX-UHFFFAOYSA-N;

CAS number : 2062-78-4;

Drug name : Orap;

Chemical formula : C28H29F2N3O;

NSC code : 170984;

ChEBI ID : CHEBI:8212;

Codes from synonyms : 09186;

Details

Origin ID

C47672;

UMLS CUI

C0031935;

Automatic exact mappings (from CISMeF team)
- fertilizers [MeSH Descriptor]
False automatic mappings
- Dimozide (substance) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Pimozide [LOINC component]
- Pimozide (substance) [SNOMED CT concept]
- Product containing pimozide (medicinal product) [SNOMED CT concept]
- pimozide [ATC Code]
- pimozide [Substance BNPC]
- pimozide [MeSH Descriptor]
- pimozide [MeSH concept]
Validated automatic mappings to BTNT
- pimozide [ATC Code]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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