Preferred Label : Phendimetrazine Tartrate;
NCIt synonyms : Morpholine, 3,4-dimethyl-2-phenyl-,(2S,3S)-,(2R,3R)-2,3-dihydroxybutanedioate(1:1); (2S,3S)-3,4-Dimethyl-2-phenylmorpholine L-( )-tartrate(1:1); Adipost;
NCIt definition : A phenylalkylamine sympathomimetic amine with appetite depressant property. Phendimetrazine
tartrate is a prodrug that is hydrolyzed to the active metabolite phenmetrazine, which
competes with norepinephrine and dopamine for their presynaptic transporters, thereby
blocks the reuptake of these monoamines at the neuronal junctions. As a result, this
prolongs activities of dopamine and norepinephrine and leads to central nervous system
(CNS) stimulation and metabolic effects, including appetite-suppression, decreased
gastric acid secretion and increased blood pressure.;
UNII : 6985IP0T80;
InChIKey : VEPOHXYIFQMVHW-PVJVQHJQSA-N;
CAS number : 50-58-8; 21102-82-9;
Drug name : Statobex-G; Plegine; Phenazine; Bontril; Metra; Sprx-105; Sprx-3; Statobex; X-Trozine;
Chemical formula : C12H17NO.C4H6O6;
NSC code : 91526;
Origin ID : C47667;
UMLS CUI : C0148932;
Automatic exact mappings (from CISMeF team)
- Currated CISMeF NLP mapping
- See also inter- (CISMeF)
- Semantic type(s)
- UMLS correspondences (same concept)
- Validated automatic mappings to NTBT
- concept_is_in_subset
- has_free_acid_or_base_form
- is_salt_form_of
