Pergolide Mesylate

Preferred Label : Pergolide Mesylate;

NCIt synonyms : 8beta-[(Methylthio)methyl]-6-propylergoline Monomethanesulfonate; Ergoline, 8-((Methylthio)Methyl)-6-Propyl-, Monomethanesulfonate, (8Beta)-;

NCIt definition : A semi-synthetic ergot derivative and a dopamine agonist with antiparkinson property. Pergolide mesylate binds to and activates dopamine receptor subtypes D1 and D2, resulting in prolactin secretion inhibition, transient increase in serum concentration of growth hormone, and decrease in serum concentration of luteinizing hormone. Direct stimulation of postsynaptic dopamine receptors in the nigrostriatal system, may account for this agent's antiparkinson activity.;

UNII : 55B9HQY616;

InChIKey : UWCVGPLTGZWHGS-ZORIOUSZSA-N;

CAS number : 66104-23-2;

Drug name : Permax;

Molecule name : LY127809;

Chemical formula : C19H26N2S.CH4O3S;

NSC code : 319773;

ChEBI ID : CHEBI:8021;

Détails

Origin ID

C47665;

UMLS CUI

C0031008;

Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Pergolide Mesylate [International Nonproprietary Name]
- Pergolide Mesylate [MeSH concept]
- Pergolide mesilate (substance) [SNOMED CT concept]
- pergolide mesylate [Substance BNPC]
Validated automatic mappings to NTBT
- pergolide [MeSH Descriptor]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_free_acid_or_base_form
- Pergolide [NCIt concept]
is_salt_form_of
- Pergolide [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

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