NCIt definition : The long-acting benzathine salt form of penicillin G, a broad-spectrum penicillin
antibiotic. Penicillin G benzathine binds to penicillin binding proteins (PBP), the
enzymes that catalyze the synthesis of peptidoglycan, a critical component of the
bacterial cell wall. This leads to the interruption of cell wall synthesis, consequently
leading to bacterial cell growth inhibition and cell lysis.;