" /> Nitazoxanide - CISMeF





Preferred Label : Nitazoxanide;

NCIt synonyms : Benzamide, 2-(acetyloxy)-N-(5-nitro-2-thiazolyl)-; Salicylamide, N-(5-nitro-2-thiazolyl)-, Acetate(Ester);

NCIt definition : A synthetic benzamide with antiprotozoal activity. Nitazoxanide exerts its antiprotozoal activity by interfering with the pyruvate ferredoxin/flavodoxin oxidoreductase dependent electron transfer reaction, which is essential to anaerobic energy metabolism. PFOR enzyme reduces nitazoxanide, thereby impairing the energy metabolism. However, interference with the PFOR enzyme-dependent electron transfer reaction may not be the only pathway by which nitazoxanide exhibits antiprotozoal activity. Nitazoxanide is active against Giardia lamblia and Cryptosporidium parvum.;

UNII : SOA12P041N;

InChIKey : YQNQNVDNTFHQSW-UHFFFAOYSA-N;

CAS number : 55981-09-4; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 55981-09-4 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Alinia;

Chemical formula : C12H9N3O5S;

NSC code : 697855;

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18/05/2024


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