Nitazoxanide - CISMeF

Preferred Label : Nitazoxanide;

NCIt synonyms : Benzamide, 2-(acetyloxy)-N-(5-nitro-2-thiazolyl)-; Salicylamide, N-(5-nitro-2-thiazolyl)-, Acetate(Ester);

NCIt definition : A synthetic benzamide with antiprotozoal activity. Nitazoxanide exerts its antiprotozoal activity by interfering with the pyruvate ferredoxin/flavodoxin oxidoreductase dependent electron transfer reaction, which is essential to anaerobic energy metabolism. PFOR enzyme reduces nitazoxanide, thereby impairing the energy metabolism. However, interference with the PFOR enzyme-dependent electron transfer reaction may not be the only pathway by which nitazoxanide exhibits antiprotozoal activity. Nitazoxanide is active against Giardia lamblia and Cryptosporidium parvum.;

UNII : SOA12P041N;

InChIKey : YQNQNVDNTFHQSW-UHFFFAOYSA-N;

CAS number : 55981-09-4;

Drug name : Alinia;

Chemical formula : C12H9N3O5S;

NSC code : 697855;

Details

Origin ID

C47637;

UMLS CUI

C0068788;

Automatic exact mappings (from CISMeF team)
- Product containing nitazoxanide (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Nitazoxanide [LOINC component]
- Nitazoxanide (substance) [SNOMED CT concept]
- Product containing nitazoxanide (medicinal product) [SNOMED CT concept]
- nitazoxanide [ATC Code]
- nitazoxanide [MeSH concept]
- nitazoxanide [MeSH Supplementary Concept]
- o-[n-(5-nitrothiazol-2-yl)carbamoyl]phenyl acetate [Substance BNPC]
Validated automatic mappings to BTNT
- nitazoxanide [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt COVID-19 Agent Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients