" /> Naratriptan Hydrochloride - CISMeF





Preferred Label : Naratriptan Hydrochloride;

NCIt synonyms : N-methyl-3-( 1-methyl-4-piperidinyl)-1H-indole-5-ethanesulfonamide Monohydrochloride;

NCIt definition : The hydrochloride salt form of naratriptan, a sulfonamide with selective serotonin (5-HT) 1 receptor agonistic activity and anti-migraine property. Naratriptan hydrochloride binds selectively and with high affinity to the 5-HT1D and 5-HT1B receptor subtypes. Activation of these 5-HT1D/B receptors located on intracranial blood vessels leads to vasoconstriction and provides relief of migraine headaches. Naratriptan hydrochloride may also exerts its effect by stimulation of 5-HT1D/1B receptors on sensory nerve endings in the trigeminal system thereby decreasing the release of pro-inflammatory neuropeptides.;

UNII : 10X8X4P12Z;

InChIKey : AWEZYKMQFAUBTD-UHFFFAOYSA-N;

CAS number : 143388-64-1;

Drug name : Amerge;

Molecule name : GR 85548A;

Chemical formula : C17H25N3O2S.HCl;

ChEBI ID : CHEBI:7479;

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01/06/2025


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