" /> Nalbuphine Hydrochloride - CISMeF





Preferred Label : Nalbuphine Hydrochloride;

NCIt synonyms : (5alpha,6alpha)-17-(Cyclobutylmethyl)-4,5-epoxymorphinan-3,6,14-triol Hydrochloride; N-Cyclobutylmethyl-14-hydroxydihydronormorphine Hydrochloride;

NCIt definition : The hydrochloride salt form of nalbuphine, a synthetic phenanthrene opioid with opiate agonist and antagonist effects, used to treat moderate to severe pain and provide preoperative and postoperative analgesia and sedation. Nalbuphine hydrochloride binds to kappa-, mu- and delta-opioid receptors but not to sigma-opioid receptors. This opioid exerts its analgesic actions primarily through kappa-opioid-receptor agonism and partially through mu-opioid receptor agonism.;

UNII : ZU4275277R;

InChIKey : YZLZPSJXMWGIFH-BCXQGASESA-N;

CAS number : 23277-43-2;

Drug name : Nubain;

Chemical formula : C21H27NO4.HCl;

ChEBI ID : CHEBI:7455;

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09/05/2025


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