Methsuximide - CISMeF

Preferred Label : Methsuximide;

NCIt synonyms : Succinimide, N,2-dimethyl-2-phenyl-; 1,3-Dimethyl-3-phenyl-2,5-dioxopyrrolidine;

NCIt definition : A succinimide with anticonvulsant properties. Although the exact mechanism of action of methsuximide is unclear, it is thought to increase the seizure threshold and suppress the paroxysmal three-cycle-per-second spike-and-wave pattern seen with absence (petit mal) seizures. The frequency of attacks is reduced by depression of nerve transmission in the motor cortex and elevation of the threshold of the CNS to convulsive stimuli, probably due to direct modification of membrane function in excitable cells and/or alteration of chemically mediated neurotransmission.;

UNII : 0G76K8X6C0;

InChIKey : AJXPJJZHWIXJCJ-UHFFFAOYSA-N;

CAS number : 77-41-8;

Drug name : Celontin;

Chemical formula : C12H13NO2;

Details

Origin ID

C47613;

UMLS CUI

C0109002;

Automatic exact mappings (from CISMeF team)
- Mesuximide [ICHI extension code]
See also inter- (CISMeF)
- Product containing mesuximide (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Mesuximide [ICD-11 Extension code]
- Mesuximide (substance) [SNOMED CT concept]
- Methsuximide [LOINC component]
- Product containing mesuximide (medicinal product) [SNOMED CT concept]
- mesuximide [ATC Code]
- methsuximide [Substance BNPC]
- methsuximide [MeSH Supplementary Concept]
- methsuximide [MeSH concept]
- methsuximide [SNOMED Notion]
Validated automatic mappings to BTNT
- mesuximide [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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