Preferred Label : Methenamine Hippurate;
NCIt synonyms : Hexamethylene Tetramine Hippurate; Hippramine; Viapta; Glycine, N-benzoyl, compound with 1,3,5,7-tetraazatricyclo(3.3.1.1(sup 3,7))decane(1:1);
NCIt definition : The hippurate salt form of methenamine, a prodrug and inactive weak base that slowly
hydrolyzes in acidic urine to ammonia and the effective, urinary tract antiseptic
formaldehyde. Formaldehyde probably exerts its antibacterial effect by denaturation
of protein. Depending on the urinary concentrations, formaldehyde is either bactericidal
or bacteriostatic. Formaldehyde urinary concentrations are dependent on urine pH,
volume, and flow rate. Formaldehyde acts as an antibacterial agent against gram-positive
and gram-negative organisms.;
UNII : M329791L57;
InChIKey : ROAIXOJGRFKICW-UHFFFAOYSA-N;
CAS number : 5714-73-8;
Drug name : Urex;
Chemical formula : C9H9NO3.C6H12N4;
Origin ID : C47610;
UMLS CUI : C0066105;
Currated CISMeF NLP mapping
- Semantic type(s)
- UMLS correspondences (same concept)
- concept_is_in_subset
- has_free_acid_or_base_form
- is_salt_form_of
