NCIt definition : The hydrochloride salt form of methamphetamine, an amphetamine and sympathomimetic
amine with CNS stimulating properties. Methamphetamine hydrochloride acts by facilitating
the release of catecholamines, particularly noradrenaline and dopamine, from nerve
terminals in the brain and inhibits their uptake. This leads to an increase in synaptic
concentration of these neurotransmitters and results in an increase of motor activity,
causes euphoria, mental alertness and excitement and suppresses appetite. Methamphetamine
hydrochloride causes dependence and may cause an increase in heart rate and blood
pressure.;