Mebendazole - CISMeF

Preferred Label : Mebendazole;

NCIt synonyms : (5-Benzoyl-1H-benzimidazol-2-yl)-carbamic Acid Methyl Ester; Methyl 5-benzoyl benzimidazole-2-carbamate;

NCIt definition : A synthetic benzimidazole derivate and anthelmintic agent. Mebendazole interferes with the reproduction and survival of helminths by inhibiting the formation of their cytoplasmic microtubules, thereby selectively and irreversibly blocking glucose uptake. This results in a depletion of glycogen stores and leads to reduced formation of ATP required for survival and reproduction of the helminth. This eventually causes the helminths death.;

UNII : 81G6I5V05I;

InChIKey : OPXLLQIJSORQAM-UHFFFAOYSA-N;

CAS number : 31431-39-7;

Drug name : Vermox;

Molecule name : R 17635;

Chemical formula : C16H13N3O3;

NSC code : 184849;

ChEBI ID : CHEBI:6704;

Details

Origin ID

C47595;

UMLS CUI

C0025023;

Currated CISMeF NLP mapping
- Mebendazole [ICD-11 Extension code]
- Mebendazole (substance) [SNOMED CT concept]
- Product containing mebendazole (medicinal product) [SNOMED CT concept]
- mebendazole [Substance BNPC]
- mebendazole [MeSH Descriptor]
- mebendazole [MeSH concept]
- mebendazole [SNOMED Notion]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Mebendazole [ICD-11 Extension code]
- Mebendazole (substance) [SNOMED CT concept]
- Product containing mebendazole (medicinal product) [SNOMED CT concept]
- mebendazole [ATC Code]
- mebendazole [Substance BNPC]
- mebendazole [MeSH concept]
- mebendazole [MeSH Descriptor]
- mebendazole [SNOMED Notion]
Validated automatic mappings to BTNT
- mebendazole [ATC Code]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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